Eyeo Festival has uploaded a number of videos of keynotes from Casey Reas, Ben Fry, Robert Hodgin, Paola Antonelli and others:
Eyeo2012 - Casey Reas from Eyeo Festival on Vimeo.
Eyeo2012 - Robert Hodgin from Eyeo Festival on Vimeo.
Eyeo2012 - Ben Fry from Eyeo Festival on Vimeo.